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A new medical method may help vascular disease

Friday, 15 June 2012
Researchers at the Sahlgrenska University Hospital in Göteborg have managed to implant a blood vessel made from a patient’s own stem cells in a ten year old, sick girl. One year after surgery she now is doing pretty fine making the researchers to hope that this could be a method to assist patients who need bypass surgery.

The process involves approach, in making the vein perform better  took three to four weeks, according to Michael Olausson, a professor at the Transplantation Center at the hospital. The vein for the girl was obtained from a donation from a deceased person, reports radio Sweden.

“Then we have removed all cells and all the genetic material, and after that we have brought stem cells from the patient who will receive the blood vessel and then grow this vessel out again,” says Michael Olausson, Professor and Director of the Transplant Center at the Sahlgrenska University Hospital in Gothenburg to radio Sweden.

At the moment, Michael Olausson and his team believe that the approach could be of great help to many people with plug formation in their blood vessels and that they need to undergo a so-called "bypass surgery".

Asked how important is it that the patient's own stem cells are included in the vein? Michael Olausson replied that it has to do with the immune system recognizing the tissue as its own and thus will not reject it. For him and the patient, it's a big advantage. All the medications that are normally given to avoid the body rejecting the new cell is very powerful and can cause side effects, so it is desirable to avoid them.

He adds that this new method is also very important so that “we’ll be able to solve problem around such things as hearts or kidneys in the future. The next big step for us is probably a work around to get arteries to function well. This opens the door and then maybe, be able to produce whole organs,” says Michael Olausson.
By Scancomark.se Team




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Denmark winning the Scandinavian leadership battle of Pharmaceutical development

Monday, 06 February 2012
While the Swedish pharmaceutical industry is waning, worker here are gradually moving south to Denmark where the sector there is booming and had over taken Sweden.  
 
It had now be contented that the Pharmaceutical sector is a sector that will bring Denmark back to its best because of the design f the sector in Denmark characterised by  its smaller holder schemes and various forms of funds and foundation led research.
 
This is not so in Sweden where there it has the tradition to rely on big money and sprawling establishments that makes shareholder to pressurise such establishment with traditionally have the tendency to harbour uncertainty. In Sweden they are forced to produce results by all means.
 
As Astra Zeneca recently announced the dismissal of many workers, the Danish pharmaceuticals such as Lundbeck are making impressive in route into gaps being lost by the Swedish giants. As such they are attracting Swedish medical researchers who are living on the border and crossing to the Denmark to work daily.
 
According to the Öresund Institute, today some 700 Swedes commute to work within the Danish biotechnology and pharmaceutical industry, which is growing fast.
Since 1998, the two big companies, Novo Nordisk and Lundbeck, have increased their workforce by 70 percent to over 15 000 people. Within the same period, the two big pharmaceutical in Sweden, Astra Zeneca and Pharmacia Upjohn, have declined by almost 20 percent to 12 000 reports radio Sweden.
 
The Danish success has been driven according to Jan Edling, an analyst at state innovation agency, Vinnova, by long-term and stable ownership.
 
There is encouragement, growth and no shareholders putting pressures on the rather smaller cap companies here.
As such research and development in Denmark is ahead of Sweden. In the current situation, the Danes have 140 products in ‘Phase 1 tests, compared with about 75 in Sweden.
 
In Denmark, it is believed that there is stable ownership of the pharmaceuticals development because they are kept in funds and foundations which have an impact on the ownerships putting limited pressures on things like prices.
 
Some companies have sought other options which instead of merging with others to grow big with the aim of gaining competitive advantage and eliminate competitors, have perhaps made contract to share the risk when it comes to producing a drug in the late phase. Looking at alternative solutions instead of becoming a huge business, something Sweden always wants to be is not a common feat in Denmark and this explains their success.
By Scancomark.se Team
 
 
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