Men with low fertility have less risk of cancer – Swedish research show
Friday, 27 January 2012
Men with reduced fertility have a significantly lower risk of
developing prostate cancer than other men, according to a new Swedish
study. Researchers have also found a genetic link which opens up new
treatments and better prevention of cancer. The results are reported to
be promising, according to radio Sweden report.
“I think they are incredibly exciting, they lie as a foundation for new
research,” says Dr. Yvonne Lundberg Giwercman at Lund University to
The researchers compared 450 men with prostate cancer with an equal
number of healthy men and found that men who have difficulty having
children run half as likely to get prostate cancer.
It was also
found that the explanation may lie in the genes, when identified, two
gene variants that affect both male and female sex hormones and the
ability to take up the environmental toxin dioxin, which reduces
fertility showed up.
This is important new knowledge, according to researcher Yasir Ruhayel.
“These genetic hereditary factors could possibly be used to estimate
the risk that one should suffer for the disease later,” he says.
10,000 men are diagnosed with prostate cancer each year in Sweden. More
than 2000 die from the disease and that means, a little pointedly, to
just over 7000 men treated unnecessarily.
“The focus on breast cancer research has led to significantly
improvement in patient outcomes, while research on prostate cancer has
lagged behind,” says Yasir Ruhayel, adding that “it’s a delay of up to
two decades compared to breast cancer.”
The researchers are initiating more studies on more men to further
investigate the genetic relationships and to more securely identify the
genes that reduce the risk of prostate cancer.
In the Swedish study it was examined also whether there were lifestyle
factors that increase the risk of prostate cancer, but to strong
conclusion could be gathered from that side of the study.
At present, it is thus the genetic trail that is most interesting.
“Heredity plays a role, it is known. Otherwise, there are not so many
things we know,” says Yvonne Lundberg Giwercman of Lund University to
By Scancomark.se Team